Neuroimaging · Neuroinformatics · Neuroscience
Sadegh Ghaderi MSc, PhD
Postdoctoral Fellow in Neuroimaging and Neuroinformatics
The Neuro/Montreal Neurological Institute-Hospital
McConnell Brain Imaging Centre, MNI · McGill University
I am currently a postdoctoral fellow at The Neuro (Montreal Neurological Institute-Hospital) and McConnell Brain Imaging Centre, McGill University, conducting research in the Neuroinformatics for Personalized Medicine Lab. With a robust academic background encompassing radiology, medical imaging, and neuroimaging (from BSc to PhD), my work leverages 7-Tesla MRI and generative computational models to characterize early microstructural changes in Parkinson’s disease and other neurodegenerative conditions.
7T / qMRISUBCORTICAL
IronMyelinWaterNetworks
79publications listed
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Research focus
Imaging biology across scales
My work connects MRI physics, computational modeling, and clinical neuroscience to study neurodegenerative disease.
My expertise bridges MRI physics with clinical applications, employing multimodal data integration—combining high-resolution imaging with omics and clinical phenotypes—to map iron, myelin, and water content in the brain, especially in subcortical nuclei. I have experience utilizing advanced neuroimaging techniques, including structural MRI, QSM, DTI, and fMRI, to investigate neurodegeneration and neuroinflammation.
My ongoing research focuses on integrating artificial intelligence with mechanistic modeling to develop open-science, AI-driven diagnostic tools that translate complex multi-omics and imaging data into precise clinical biomarkers.
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Selected publications
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Functional adaptive longitudinal reorganization of superior parietal lobule networks in amyotrophic lateral sclerosis: Evidence suggesting compensatory mechanisms
Hippocampal Subfield Integrity and Age‐Driven Neural Correlates of Appetite Loss in Amyotrophic Lateral Sclerosis
Magnetic susceptibility source separation (χ-separation) in quantitative susceptibility mapping
Research portfolio
Selected research projects
Current and completed work spanning neurodegeneration, quantitative MRI, and medical image analysis.
OngoingFebruary 2026 – Present
Current Postdoctoral Research in Neuroimaging and Neuroinformatics
Early diagnosis and PM in Parkinson’s disease and other neurodegenerative conditions.
Project detailsCompleted2019 – 2024
PhD Dissertation — Evaluation of Structural and Functional Brain Changes in Amyotrophic Lateral Sclerosis
Evaluation of structural and functional brain changes in ALS to identify disease biomarkers and support targeted treatment.
Project detailsCompleted2016 – 2019
MSc Thesis — MRI Properties of a Gadolinium-Loaded Aluminosilicate Nanocomposite
Magnetic resonance imaging characterization of a gadolinium (III)-loaded aluminosilicate nanocomposite containing doxorubicin with a folic acid coating.
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For research discussions, invited talks, reviewing, or collaboration enquiries:
sadegh.ghaderi@mcgill.ca Contact details